Prof. Rukman Hertadi
Research Focus

Research Areas

Exploring four key pillars of physical biochemistry and biomolecular innovation from Indonesian extremophilic bacteria.

Area 1

Biomolecular Exploration from Halophilic Bacteria

Indonesia memiliki banyak habitat halofilik yang masih sangat terbuka untuk dieksplor lebih intensif. Halofil adalah mikroorganisme yang dapat hidup pada kondisi ekstrem dengan kadar garam tinggi, pH tinggi, dan temperatur tinggi. Penelitian kami fokus pada isolasi bakteri dari habitat ekstrem Indonesia dan karakterisasi biomolekul potensial seperti Biosurfactant (Rhamnolipid), Bioplastic (PHB), Ectoine, dan Levan.

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Area 2

Protein Stability and Dynamics

Studi tentang stabilitas dan dinamika protein menggunakan simulasi molecular dynamics dan teknik biokimia fisika. Penelitian utama meliputi DNA Polymerase I ITB-1, Thermostable alkaline lipase, dan Enzyme Engineering untuk meningkatkan stabilitas dan aktivitas enzim.

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Area 3

Computational Biochemistry

Menggunakan Molecular Dynamics (MD) simulation, Molecular Docking, Homology Modeling, dan Bioinformatics analysis untuk Drug Design (Carbonic Anhydrase II inhibitors, Proteasome inhibitors), Protein Modeling, dan Machine Learning Applications (BiCaps-DBP untuk prediksi DNA-binding proteins).

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Area 4

Applied Biotechnology

Aplikasi biomolekul untuk Enhanced Oil Recovery (EOR), Cosmetic Applications (nanopartikel berbasis rhamnolipid untuk perlindungan kulit multifungsi), Pharmaceutical Applications (oral insulin delivery systems), dan Environmental Applications (bioconversion of palm oil waste, corrosion inhibitors).

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Innovation

Prototypes & Products

Translating research into practical applications and commercial products for industry impact.

PROTOTYPE

Biosurfactant for EOR

Biosurfactant derived from halophilic bacteria for Enhanced Oil Recovery applications in petroleum industry.

Application: Energy Sector
PRODUCT

Ectoin Stabilizer

Ectoin-based protein stabilizer for pharmaceutical and cosmetic applications, derived from Halomonas elongata.

Application: Healthcare & Cosmetics
PROTOTYPE

Levan Biopolymer

Levan production from Chromohalobacter japonicus for food industry and health applications.

Application: Food & Health